Three of the scenarios are
unconfounded (for difference-in-differences) because treatment assignment is (1) completely random (i.e., unrelated to group mean levels or trends), (2) correlated only with group mean outcome level, or (3) correlated with group mean level of a time-varying covariate that is in turn correlated only with the group mean outcome level.
However, although our group and others published on several other genetic variants in LPL with moderately increased triglycerides and associated cardiovascular disease, this was before the age of "Mendelian randomization studies" and the understanding that such
unconfounded studies free of reverse causation demonstrated causality.
Under the causal diagram in Figure 1A, adjustment for Z is sufficient to estimate an
unconfounded association between X and Y.
Consistent with previously recommended statistical practice, significant two- or three-way interactions were followed by
unconfounded pairwise post hoc comparisons and evaluated for significance using the Bonferroni/Dunn correction [5, 31, 32].
Shaw et al., "Serum ferritin iron, a new test, measures human body iron stores
unconfounded by inflammation," Stem Cells, vol.
Because genotype is not modifiable by disease, a genetic instrument can be used as an model for an exposure, and "Mendelian randomization generates unbiased,
unconfounded effect estimates that are sometimes taken as evidence of a causal role," Jon White, PhD, of University College London and his coinvestigators explained.
But if these statutes do not impact the takeover threat, or if (re-)incorporation decisions render a firm's exposure to them endogenous, or if the firms incorporated in states that never adopted an ATS are not really comprable to those incorporated in states that did adopt ATSs, the single best source of
unconfounded evidence for how the takeover threat affects real behavior becomes useless.
Then in Part III we describe a study designed to test these conjectures in a manner
unconfounded by the defects in existing investigations of judicial decisionmaking.
(3.) Herbert V, Jayatilleke E, Shaws, Rosman A S, Giardina P, Grady R W, Bowman B, Gunter E W, Serum Ferritin Iron, a new test, measures human body iron stores
unconfounded by inflammation.