Typhoid fever complicated by chloramphenicol toxicity, ataxia and psychosis
Trevett, A.J.; Naraqi, S.; Wembri, J.
Papua and new Guinea Medical Journal 35(3): 205-209
1992
ISSN/ISBN: 0031-1480 PMID: 1296424 Document Number: 390374
A case of typhoid fever complicated by pancytopenia, cerebellar signs and psychosis is described. The association of reversible marrow suppression with chloramphenicol treatment and its clinical features are outlined. The features of cerebellar dysfunction and of psychosis in patients with typhoid are described. Recommendations are made to help identify the problem of chloramphenicol-induced marrow suppression when it occurs.