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Obstructive jaundice secondary to primary biliary involvement with Hodgkin's disease

Martin, K.R.; Moore, T.J.; Wright, R.A.

American Journal of Gastroenterology 87(9): 1194-1195

1992

ISSN/ISBN: 0002-9270
PMID: 1519580
Document Number: 390063
A 41-yr-old man presented with jaundice, night sweats, and weight loss. The patient had been on phenytoin for seizure disorder. The drug was discontinued, and a diminution of bilirubin and transaminases occurred over several weeks. Percutaneous liver biopsy revaled cholestasis at the time of maximal hyperbilirubinemia. Recurrent jaundice ensued several weeks later, and an ERCP revealed a common bile duct lesion. Laparotomy revealed Hodgkin's disease involving the common bile duct and periportal node. This cause represents the first report of extrahepatic biliary obstruction from Hodgkin's disease.

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