Brain natriuretic peptide (BNP) -like immunoreactivity in the central nervous system of the crested newt
Franzoni, M.F.; Canonaco, M.; Frova, A.; Tavolaro, R.
European Journal of Histochemistry Ejh 36(4): 455-466
1992
ISSN/ISBN: 1121-760X PMID: 1283833 Document Number: 389786
The distribution of brain natriuretic peptide (BNP)-like immunoreactivity (ir) was studied in the brain of a urodele amphibian, the crested newt Triturus carnifex Laur. BNP-like immunoreactive neurons were found mainly in the caudal hypothalamus (retro- and supra-chiasmatic areas) and in the preoptic area. A widespread innervation throughout the brainstem as far as the spinal cord was also observed. By double immunostaining (after section incubation with a-BNP and a-tyrosine hydroxylase-TH-antibodies), close topographical relationships between BNP-like and TH-like immunoreactive neurons within the hypothalamus were found.