pro re nata

Group A (grey box on the plot; group A consists of treatment-naive patients undergoing monthly loading phase) and group B (stripped box; group B consists of treated patients undergoing treatment according to a pro re nata regimen).

Standard regimen of pharmacotherapy during alcohol withdrawal Type of drug Number of clinicians prescribing various substitution drugs for alcohol withdrawal (N = 58) As standard In selected PRN, Do not use, treatment, patients, * ([dagger]) n (%) n (%) n (%) n (%) Benzodiazepines 50 (86.2) 4 (6.9) 1 (1.7) 3 (5.2) Clothiapine 18 (31.0) 14 (24.1) 10 (17.2) 16 (27.6) Beta-blockers 5 (8.6) 8 (13.8) 7 (12.1) 36 (62.1) Anticonvulsants 6 (10.3) 21 (36.2) 4 (6.9) 27 (46.6) Antidepressants 14 (24.1) 12 (20.7) 2 (3.4) 33 (56.9) * In selected patients: based on underlying comorbidity; +PRN (pro re nata): as required for symptoms appearing during treatment.

The most common other abbreviations that still linger on are hs (hora somni) for 'at the hour of sleep' and prn (pro re nata) for 'as necessary', and also the instructions starting at the top with Rx (for recipe) and sig for 'label' (signature).

The safe and efficacious use of Pro Re Nata medication can compliment the development of multimodal support plans to optimize outcome in this context.