After 6 months, the researchers tested a snip of
lymphoid tissue from the tonsils of the patients.
(2002) Nasal-associated
lymphoid tissue is a mucosal inductive site for virus-specific humoral and cellular immune responses.
6) All structures containing excess of
lymphoid tissue normally have a tendency to undergo involution after maturity has been reached.
Most cases of primary lymphoma of the lung are of B-cell lineage, and the disease is frequently located in the bronchus-associated
lymphoid tissue. These neoplasms are most commonly seen in adults with a median age of about 60 years and rarely develop in children.
MCL is one of the less common B-cell subtypes of NHL and develop from non-germinal center B-cells within the mantle zone of the lymph nodes and
lymphoid tissues. (1) The underlying cytogenetics is due to translocation t(11;14)(q13;q21), which eventually results in overexpression of cyclin D1, a cell cycle protein not usually expressed in lymphoid cells; therefore, disrupting the central cell cycle pathway balance resulting in MCL.
* Multicentric (in lymph nodes throughout the body as well as organs with concentrations of
lymphoid tissue)
In 1724 Santorini first described the nasopharyngeal aggregate of
lymphoid tissue and Wilhelm coined the term "adenoid" for nasopharyngeal vegetations1.
Immunohistochemistry demonstrated strongly positive stained with CD20 [Figure 1]f, confirming the diagnosis of lymphoma of mucosal-associated
lymphoid tissue (MALT).
In this context, important differences exist, especially in the diversity of the
lymphoid tissue. For instance, the bursa of Fabricius is present in hens but not in mammals.
Bovine lymphosarcoma is a malignant neoplastic proliferation
lymphoid tissue, disease affecting cattle of all ages without regards for sex or breed.
The intestinal glands were greatly developed in the ileum, lymphoid nodules were observed in the mucosa, and diffuse
lymphoid tissue was distributed in the lamina propria.
CLE criteria for gastric lymphoma were based on recent established findings as follows [10-12]: (1) darkened areas made up of small roundish cells of similar size and morphology for the mucosa-associated
lymphoid tissue (MALT) lymphoma or larger roundish cells for diffuse large B-cell lymphoma (DLBCL); abnormal cells in a dense arrangement; (2) cellular infiltrates typically affecting but not limited to the lamina propria; (3) cellular invasion of various epithelial structures; (4) altered tissue morphology to complete loss of structural integrity of the epithelium.
Harris et al., WHO Classification of Tumours of Haematopoietic and
Lymphoid Tissue, IARC, Lyon, France, 4th edition, 2008.
Primary hepatic marginal zone B cell lymphoma of mucosa-associated
lymphoid tissue (MALT) is extremely rare, representing 3% of PHL [3].
The HEV basal lamina also functions as a guidance structure for the directional trafficking of lymphocytes from HEVs into the
lymphoid tissue parenchyma.
