Related Conditions

Obtaining an accurate diagnosis of bipolar disorder—as with many other complex medical conditions—usually takes time and patience to sort out and address effectively. Co-occurring psychiatric and medical conditions, and other related health diagnoses, complicate a person’s diagnosis and treatment plan—and their daily life. Understanding the various ways in which symptoms coincide and interact allows for better outcomes for overall health.

Co-Occurring Psychiatric Conditions

It’s common for people with bipolar disorder to have one or more psychiatric conditions. However, with separate diagnoses and treatment plans, it’s possible to manage overlapping symptoms and improve stability.
  1. Attention Deficit Hyperactivity Disorder (ADHD)
  2. Anxiety Disorders
  3. Addiction Disorders
  4. Eating Disorders
  5. Obsessive Compulsive Disorder (OCD)
  6. Post-Traumatic Stress Disorder (PTSD)
  7. Personality Disorders
  8. Seasonal Affective Disorder (SAD)

Coexisting Medical Conditions

Many individuals with bipolar will also be diagnosed with health-related challenges that can impact their quality of daily life.
  1. Cardiovascular Disease
  2. Chronic Pain
  3. Metabolic Syndrome (including type II diabetes & obesity)
  4. Migraine

Related Diagnoses

Often, there are related conditions with symptoms that mimic bipolar and can lead to initial misdiagnosis.
  1. Major Depressive Disorder (MDD)
  2. Psychosis
  3. Tardive Dyskinesia (TD) or akathisia
  4. Schizoaffective Disorder/Schizophrenia

Medically Reviewed by Allison Young, MD

 

Blogs and Articles
tardive dyskinesia warning signs early detection treatment

Early Signs of Tardive Dyskinesia

Robin L. Flanigan
March 17, 2026

Early symptoms of tardive dyskinesia can be subtle. Here’s how screening, treatment, and support can make a difference. Key Takeaways Tardive dyskinesia is an involuntary neurological condition characterized by uncontrollable, repetitive body movements. It can cause lip-smacking, tongue-thrusting, jaw-clenching, torso-twisting, or other mannerisms that may be subtle and mildly embarrassing, or painful and debilitating. While...

READ MORE
An illustration shows a human brain as a maze and two doctors walking through to depict challenges in diagnosing tardive dyskinesia.

Why Tardive Dyskinesia Is Often Underdiagnosed

Denise Mann
February 20, 2026

Tardive dyskinesia can appear months or years after medication starts, and subtle early movements are easy to dismiss without routine AIMS checks. Key Takeaways _______________ When Dawn L. was tapering off medication to treat lingering symptoms of bipolar depression in 2019, she started to experience severe jaw clenching and trouble swallowing. The New Hampshire woman,...

READ MORE

How Therapy Helps People With Tardive Dyskinesia

Stephanie Stephens
February 10, 2026

From speech to motor skills, see how a therapy team supports those with bipolar disorder facing movement issues. Key Takeaways _______ A diagnosis of tardive dyskinesia means learning to expect the unexpected, accepting what you can’t control, and working skillfully within those parameters. As the National Institute of Neurological Disorders and Stroke (NINDS) explains, this...

READ MORE
A woman with bipolar disorder is unsure if she has tardive dyskinesia or akathisia.

Are Your Movement Symptoms Akathisia or Tardive Dyskinesia?

Julie Stewart
December 17, 2025

Both can appear after taking antipsychotic medication, but their timing and treatments differ. Knowing the distinction can help you get the right support. Akathisia and tardive dyskinesia are neurological movement disorders that can develop as side effects of certain dopamine-blocking medications, particularly antipsychotics. Because both can involve restlessness, twitching, or repetitive movements, they’re often mistaken...

READ MORE
A woman with tardive dyskinesia uses Artifical Intelligence on her phone app to help medical professionals with a diagnosis.

7 Ways AI Is Reshaping the Diagnosis and Treatment of Tardive Dyskinesia

Julie Stewart
November 10, 2025

Artificial intelligence is helping doctors spot subtle early signs of tardive dyskinesia, so fewer cases go undiagnosed and untreated. Tardive dyskinesia affects hundreds of thousands of people, yet it often goes unrecognized. The symptoms can be easy to overlook at first — a subtle lip twitch, a slight hand movement, or a bit of restlessness...

READ MORE
Aspartame in granular and tablet form for an article on possible negative side effects of tardive dyskinesia.

Could Aspartame Play a Role in Tardive Dyskinesia?

Julie Stewart
October 7, 2025

Aspartame is considered safe within daily limits, yet researchers are studying whether it may affect tardive dyskinesia. Here’s what early findings suggest. Aspartame is one of the most commonly used artificial sweeteners, found in diet sodas, sugar-free gum, and low-calorie foods. While regulatory agencies around the world consider it safe when consumed within daily limits,...

READ MORE
black woman with bipolar disorder holds her temples with migraine pain.

When Pain Makes Bipolar Worse: The Overlap With Migraine

Donna Jackel
October 1, 2025

Migraine pain can intensify depression, anxiety, and mood symptoms in bipolar disorder. The good news is that some treatments may help with both. Key Takeaways Living with bipolar disorder already feels like a demanding job, requiring constant attention and effort to manage symptoms effectively. Yet when a neurological disease like migraine enters the picture, the...

READ MORE
A bottle of Vitamin E to depict a possible benefit for tardive dyskinesia symptoms.

Can Vitamin E Really Help Tardive Dyskinesia? What the Research Shows

Julie Stewart
September 25, 2025

Some studies suggest vitamin E may help ease symptoms of tardive dyskinesia — but how strong is the evidence, and what does it really tell us? Note: The U.S. Food and Drug Administration (FDA) does not approve supplements for safety or effectiveness. Talk to a healthcare professional about whether a supplement is the right fit...

READ MORE
A collage to depict the best foods to help symptoms of tardive dyskinesia.

The 5 Best Foods to Help Tardive Dyskinesia — and What to Avoid

Julie Stewart
September 10, 2025

While eating well won’t cure tardive dyskinesia, choosing the right foods may help ease symptoms and support brain health. What you eat can’t cure tardive dyskinesia, but research shows that specific nutrients may support brain and nerve health, possibly easing some of the movement symptoms linked to this condition. Tardive dyskinesia is a neurological disorder...

READ MORE
Grammy-nominated singer Carnie Wilson sits at a piano. She's a spokesperson to bring awareness to tardive dyskinesia.

Carnie Wilson Shines a Light on Tardive Dyskinesia

Tanya Hvilivitzky
June 16, 2025

Carnie Wilson, daughter of the late Beach Boys icon Brian Wilson, lends her voice to a campaign raising awareness of tardive dyskinesia. Few outside the mental health field have heard of tardive dyskinesia — and Carnie Wilson is out to change that. The Grammy-nominated singer and longtime mental health advocate is lending her voice to...

READ MORE
Bruce Springsteen references his depression in his songs and talks about his father's paranoid schizophrenia.

8 Bruce Springsteen Songs That Reveal a Life of Depression

bpHope
May 22, 2025

Bruce Springsteen has spent decades turning private pain into powerful music. These songs reveal how his lifelong battle with depression shaped both his art and identity. Bruce Springsteen has never shied away from talking about his lifelong experience with depression — a challenge he’s worked hard to manage for decades, even while living in the...

READ MORE
An illustration of a brain with neural activity to depict tardive dyskinesia, affecting people with bipolar disorder, among others.

What Is Tardive Dyskinesia? Symptoms, Causes, and Treatment

Julie Stewart
April 7, 2025

Tardive dyskinesia causes involuntary movements in some people taking antipsychotic medications. Here’s what you need to know about this movement disorder. Antipsychotic medications are a mainstay of bipolar disorder treatment, but for some people, these drugs come with the side effect of tardive dyskinesia. Tardive dyskinesia causes involuntary, repetitive muscle movements, often in the face,...

READ MORE
tardive dyskinesia TD natural therapy treatment

Can Natural Therapies Help Tardive Dyskinesia? Exploring the Evidence

Robin L. Flanigan
January 13, 2025

Tardive dyskinesia is a drug-induced neurological disorder characterized by involuntary movements of the face and body. The condition develops as a side effect of long-term use of antipsychotics and other medications that block dopamine receptors in the brain. People who develop this movement disorder can’t control facial movements, like tics, lip-smacking, rapid blinking, and tongue...

READ MORE
illustration of three hands pulling string from a human head - to indicate tardive dyskinesia.

What You Need to Know About Tardive Dyskinesia: Insights From Top Experts

Denise Mann
December 3, 2024

Tardive dyskinesia often goes undiagnosed. Leading experts share advice on early detection and treatment. Living with tardive dyskinesia can feel like facing an invisible challenge. This often-overlooked side effect of medications used to treat psychiatric conditions affects at least 600,000 people in the United States, according to Mental Health America. Yet despite its prevalence, many...

READ MORE
tardive dyskinesia syndrome bipolar disorder

Understanding the Different Types of Tardive Syndromes

Tanya Hvilivitzky
November 1, 2024

Experiencing unexplained movement symptoms? Discover the different tardive syndromes linked to psychiatric medications. If you’ve noticed uncontrollable, repetitive movements in your body, you might be dealing with tardive dyskinesia or another tardive disorder. This neurological condition develops after long-term use of certain medications, most commonly first and second-generation antipsychotic drugs used to manage mental health...

READ MORE

15 Celebrities Living With Depression or Anxiety

Tanya Hvilivitzky
September 5, 2024

Through their personal stories of battling depression, anxiety, and other mental health challenges, these famous figures offer reassurance to others on similar paths. In a society where mental health is often stigmatized, celebrities who speak openly about their struggles can be powerful catalysts for change. Their stories help demystify mental illness, revealing that such challenges...

READ MORE
illustration of female silouette with cloud and rain, to indicate bipolar depression.

Ask the Doctor: Understanding Bipolar Depression

Melvin G. McInnis, MD, FRCPsych
September 5, 2024

Bipolar depression shares symptoms with unipolar depression — and some physical health conditions — but different diagnoses require different treatments. The mood swings between depression and mania that characterize bipolar disorder typically occur along a continuum, with a high frequency of days with mood swings that are not necessarily extreme enough to count as an...

READ MORE
Young mother with postpartum depression sits on the sofa with her newborn.

Ask the Doctor: What Is Postpartum Depression? Risks, Symptoms, and Treatment

Maria Muzik, MD
August 20, 2024

Emotional challenges affect 80 percent of new mothers, with more than 1 in 7 experiencing postpartum depression. Recognize the signs and find the support you need. Q. I just had a baby and thought this would be the happiest time in my life. And now I feel so anxious and down all the time and...

READ MORE
A woman with long blonde hair and green dressed stands in her kitchen visibly stressed and burned out.

Restoring Balance: How to Recover From Stress and Burnout

Robin L. Flanigan
August 15, 2024

Chronic stress and burnout can sap the joy from life — but small changes over time can help you regain control. We all have different tasks to perform throughout the day, and we try our best to balance them. We manage our work life, family responsibilities, budget, screen time, diet, moods, exercise, social life, downtime,...

READ MORE
A man stands in the street holding up a green glass in front of his face. He has persistent depressive disorder.

Understanding Persistent Depressive Disorder (Dysthymia)

Robin L. Flanigan
August 8, 2024

Despite fewer symptoms than major depression, persistent depressive disorder is a chronic, serious condition impacting daily life. It seemed as if the whole town had come to the same party. People danced to a live band, kids had their faces painted, dogs ran freely. Dan, who lives in Massachusetts, had come to the neighborhood celebration...

READ MORE