IOB.ch

@IOB_ch

Researchers and Clinicians united to restore vision.

Uniuse en abril de 2018

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  1. 1 de out.

    A study to better understand the consequences of therapeutic genome editing with and , driven by Bence György, our Head of Clinical Translation, and collaborators, is now available :

    Figure 1 (Credit: Killian Hanlon) Hypothesis of AAV vector DNA integration after CRISPR-mediated DNA cleavage: after a CRISPR-induced DSB, a broken ITR gets captured by the genome; then, the vector is chewed back in some fashion, possibly by exonucleases; finally, repair enzymes facilitate the complete integration of the vector.
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  2. 27 de set.

    Gray Camp (with B Treutlein & ) reviewed how , engineering & CRISPR-Cas technologies have revolutionized the understanding of human cell phenotypes

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  3. 16 de set.

    Congratulations to Peter Maloca and his collaborators!

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  4. 16 de set.

    Carlo Rivolta is co-senior author of an article in , which shows that a previously retinal-associated protein is essential for sperm tail development and assembly.

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  5. 12 de set.

    Great video about Neuroscience for Sensory Disorders now online. Last three minutes cover attempt to prevent or treat blindness in with contribution from molecular and clinical teams. Video: ;

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  6. rechouchiou
    10 de set.

    Botond Roska received the 2019 for work on visual information processing and developing therapies to restore vision in retinal disorders. Why not check out his review on this topic:

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  7. rechouchiou
    6 de set.

    Great to meet Dr Hendrik Scholl from to talk about the challenges and advances in the treatment of retina dystrophies at . Full interview coming soon!

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  8. 6 de set.

    What’s new in and ’s contributions in Europe: Symposium today 16.30 – 18.00 room 351 at in Paris, chaired by HPNScholl and J Cunha-Vaz, and with Roundtable on Innovation in Retinal Diseases Management.

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  9. rechouchiou
    5 de set.

    Touch Ophthalmology are delighted to be meeting with Hendrik Scholl whilst attending to discuss new developments in the treatment of Full video interview to follow. Watch this space!

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  10. rechouchiou
    4 de set.
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  11. 28 de ago.

    Congratulations to Josephine Jüttner! She will receive the SWISS OphthAWARD 2019 for the best experimental work at the 112th SGO/SSO congress in Interlaken.

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  12. rechouchiou
    28 de ago.

    Gratulation! Hendrik Scholl, Professor für Ophthalmologie und klinischer Leiter des , erhält den Alfred-Vogt Preis. Es ist dies die höchste Auszeichnung in der Schweiz für Forschung in und um die Augenheilkunde.

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  13. rechouchiou
    28 de ago.

    Hohe Auszeichnungen für Basler Augenforscher: Prof. Botond Roska hat den Ungarischen Sankt-Stephans-Orden erhalten, Prof. Hendrik Scholl den Alfred-Vogt Preis zur Förderung der Augenheilkunde. Die Professoren der leiten gemeinsam das .

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  14. 21 de ago.

    Congratulations! Botond Roska received the Order of Saint Stephen, the highest distinction in Hungary, from president János Áder, who said vision-restoring may soon become a universal treasure thanks to our Molecular Director's contributions.

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  15. 20 de ago.

    This joint eight year effort of our molecular and clinical researchers to build and test 230 AAVs with unique synthetic promoter sequences for use in the is now also featured as research highlight in Nature Neuroscience:

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  16. 19 de ago.

    Just out from our Imaging Group: Validation of automated segmentation of images. The tool is available as a fully automated and cloud-based analysis method free of charge & open access!

    Illustration of the online annotation tool used for manual OCT image compartmentalization. In this example, the ILM (arrows) was segmented. The same was done for inner border of the choriocapillaris (CC) and CSI.
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  17. 2 de ago.

    Listen to the author interview podcast covering ProgStar Report#11 with HPN Scholl: Progression of Stargardt Disease as Determined by Fundus Autofluorescence Over a 12-Month Period

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  18. 2 de ago.

    In autofluorescence imaging of growth of atrophic lesions helps estimate yearly progression rate & is an efficacy marker for therapeutic interventions that aim to slow down disease progression. Read more in ProgStar Report No.11

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  19. 22 de xul.

    Another exciting result of the joint efforts of our molecular researchers & clinicians: Artificial human contain cell types and features of the adult human , creating new opportunities for modeling .

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  20. 9 de xul.

    Working closely hand in hand, our molecular and clinical researchers developed this AAV library for economic, fast and efficient cell-type targeting across species.

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