The playable characters include...
- Dracula
- Frankenstein's monster
- The Wolf Man
- The Mummy
- Creature from the Black Lagoon
- The Phantom of the Opera
- Bride of Frankenstein (whose name in life is revealed to have been Madeleine Ernestine, continuity fans!)
- The Invisible Man
- Dracula's Daughter, Countess Zaleska
- The Metaluna Mutant (from This Island Earth)
- The Mole Man King
- Dan McCormick, The Man Made Monster
- Gwynplaine, the Man who Laughs
- Weird Woman
- The Robot (from The Phantom Creeps)
Some characters who showed up in the concept art...
- Ygor (from Son of Frankenstein)
- Quasimodo
- Dr. Jekyll and Mr. Hyde
- The Creeper (from House of Horrors / The Brute Man)
- The Lamian Queen (from Cult Of The Cobra)
- Female Van Helsing
- Inspector Krogh (from Son of Frankenstein)
- Fritz, Dr Frankenstein's hunchbacked assistant (who appears to be in some sort of make shift mech suit made out of chains, wood, gates and fences)
This game provides examples of:
- Adaptational Badass: Inspector Krogh can be seen in the promo art. Only his prosthetic arm has been upgraded to a bionic hammer!
- Adaptational Villainy: In their source material, Gwynplaine and the Mole Men were tragic characters. The Mole Men were abused, forcibly mutated, and enslaved, making their anger understandable. Gwynplaine is a completely good character who is one of the most noble characters in his story despite his grotesque appearance. Their bios play them up as more monstrous - Gwynplaine is implied to be murderous while the Mole People's backstory as slaves isn't mentioned.
- Monster Mash
- Mooks: Zombies and trolls.
- Mythology Gag:
- Frankenstein's alternate skin bears a heavy resemblance to the version from Van Helsing.
- The Phantom of the Opera's default look combines elements of his traditional appearance with his The Masque of the Red Death disguise (which is also his alternate costume).
- Unlockable Content: By earning money in the game the player is able to access items, costumes and unlockable monsters.
- You Don't Look Like You: Some monster designs are modeled closely around the film versions, while others take far more artistic license: Countess Zaleska looks completely different to her actress Gloria Holden, while the Man Made Monster is much more evil-looking than the unfortunate schmuck played by Lon Chaney Jr. In some cases, the original designs are available as unlockable costumes.