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Comparative Study
. 2003 Sep;160(9):1691-3.
doi: 10.1176/appi.ajp.160.9.1691.

High blood monocyte counts and neopterin levels in children with autistic disorder

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Comparative Study

High blood monocyte counts and neopterin levels in children with autistic disorder

Thayne L Sweeten et al. Am J Psychiatry. 2003 Sep.

Abstract

Objective: Leukocyte counts and plasma neopterin levels were determined in autistic children and matched healthy comparison subjects.

Method: Blood from 31 autistic children and 28 age- and gender-matched healthy comparison subjects was analyzed for numbers of neutrophils, eosinophils, basophils, lymphocytes, monocytes, and total leukocytes and for plasma neopterin levels.

Results: The monocyte count and neopterin level were significantly higher in the autistic children than in the comparison subjects.

Conclusions: These results suggest that the immune system may be activated in some children with autism.

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