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The Tie That Binds Us? Challenging the Primacy of DNA in Kinship Studies and Re-Centring Community in Defining Human Connections across Time
Moots, Hannah M.; Tsosie, Krystal S.; Somel, Mehmet (2026-05-01)
Biological determinism continues to shape how kinship is defined, from research to repatriation proceedings. This privileging of biological relatedness reflects and reinforces dominant ‘Western’ frameworks of kinship, often sidelining culturally-specific, Indigenous, and community-centered understandings of family and social belonging. Advances in archaeogenomic technologies today offer unprecedented insight into past human societies, and these advances have the potential to forge new, multivocal, and inclu...
Genetic Circuits To Detect Nanomaterial Triggered Toxicity through Engineered Heat Shock Response Mechanism
Saltepe, Behide; Bozkurt, Eray Ulas; Haciosmanoglu, Nedim; Şeker, Urartu Özgür Şafak (2019-10-01)
Biocompatibility assessment of nanomaterials has been of great interest due to their potential toxicity. However, conventional biocompatibility tests fall short of providing a fast toxicity report. We developed a whole cell based biosensor to track biocompatibility of nanomaterials with the aim of providing fast feedback to engineer them with lower toxicity levels. We engineered promoters of four heat shock response (HSR) proteins utilizing synthetic biology approaches. As an initial design, a reporter codi...
Development of a Maintenance Policy Simulation Model for Mining Operations Using Multiple Failure Modes
Şahiner, Şahin Furkan; Gölbaşı, Onur (2025-11-11)
Madencilik faaliyetlerinde ekipman sürekliliğini sağlamak ve arıza kaynaklı duruş sürelerini en aza indirmek için etkili bakım planlaması büyük önem taşımaktadır. Bu çalışmada, çoklu arıza modları ve bunlar arasındaki bağımlılıkları dikkate alarak bakım politikalarını değerlendirmek üzere geliştirilen ayrık olay simülasyonu (DES) temelli bir model sunulmaktadır. Model, her bir bileşen için arıza ve onarım sürelerini benzeterek sistemin dinamik davranışını yansıtır. Arıza bağımlılık matrisi, meydana gelen ar...
Spatially Selective Assembly of Quantum Dot Light Emitters in an LED Using Engineered Peptides
Demir, Hilmi Volkan; Şeker, Urartu Özgür Şafak; Zengin, Gulis; MUTLUGÜN, EVREN; Sari, Emre; Tamerler, Candan; Sarikaya, Mehmet (2011-04-01)
Semiconductor nanocrystal quantum dots are utilized in numerous applications In nano- and biotechnology. In device applications, where several different material components are involved, quantum dots typically need to be assembled at explicit locations for enhanced functionality. Conventional approaches cannot meet these requirements where assembly of nanocrystals is usually material-nonspecific, thereby limiting the control of their spatial distribution. Here we demonstrate directed self-assembly of quantu...
Oxide dispersion strengthening of IN939 produced by selective laser melting
Koç, Hasan Tahsin; Kalay, Yunus Eren; Department of Metallurgical and Materials Engineering (2025-11)
Inconel 939 is a high-performance nickel-based superalloy that is used in high-temperature and high-stress applications such as aerospace, energy, and petrochemical industries. Inconel 939 is known for its good strength, corrosion resistance and creep resistance at high temperatures, making it an ideal material for harsh environments. However, there is always a need for further improvement of its properties to meet the demanding requirements of these industries. Dispersion strengthening is a well-known meth...
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