Split Liver Transplantation

The division of a donor liver into parts in order to transplant the tissue into a child or small recipient
Pros Increases the number of potential recipients
Cons Increased billiary complications—27% vs. 4% non-split

References in periodicals archive ?

In situ split liver transplantation for 2 adult recipients: A single-center experience.

Clinical Features and Clonal Origin of Diffuse Hepatocellular Carcinoma

The alternatives include split liver transplantation (SLT), in which a liver is divided up to transplant into two recipients, and living donor liver transplantation (LDLT), in which a portion of a liver from a live donor is used.

Our findings, which show that overall patient and graft survivals have improved , and that outcomes for alternatives to WLT are comparable, will hopefully influence policy for organ allocation such as greater use of split liver transplantation," said Dr Mogul.

Liver transplant options for children 'safer now'

Such strategies involve living donor liver transplantation (LDLT), split liver transplantation (SLT), and domino liver transplantation (DLT) [11, 41-45].

Abbreviations ALF: Acute liver failure ASL: Arginine succinyl lyase deficiency CND: Crigler-Najjar disease DHT: Domino hepatocyte transplantation DLT: Domino liver transplantation FAP: Familial amyloid polyneuropathy GSD: Glycogen storage disease HCC: Hepatocellular HT: Hepatocyte transplantation DLT: Living donor liver transplantation LT: Liver transplant SLT: Split liver transplantation OLT: Orthotopic liver transplantation OTD: Ornithine transcarbamylase deficiency PFIC: Progressive familial intrahepatic cholestasis TTR: Transthyretin.

Umman, "Split liver transplantation: An overview," Transplantation Proceedings, vol.

Domino Hepatocyte Transplantation: A Therapeutic Alternative for the Treatment of Acute Liver Failure

Split liver transplantation carries no increased risk of failure in either recipient, allowing transplant surgeons to safely save two lives from a single donated organ, according to new research from Boston Children's Hospital.

Split liver transplants safe for both of the recipients, study finds

Freise, "Outcomes with split liver transplantation in 106 recipients: The University of California, San Francisco, experience from 1993 to 2010," JAMA Surgery, vol.

The New Era of Transplant Oncology: Liver Transplantation for Nonresectable Colorectal Cancer Liver Metastases

Responding to the steady increase in US transplant programs practicing split liver transplantation, the United Network for Organ Sharing/Organ Procurement and Transplantation Network Ethics Committee has developed a set of voluntary guidelines for programs to follow.

"One of the paramount responsibilities of transplant surgeons is to inform recipients as to the current practices of their transplant program regarding split liver transplantation, the risks involved, the potential for increased morbidity requiring additional interventional/surgical procedures and hospital stay, and the program's outcome data regarding these procedures," the committee writes in the paper "Split Vs.