ITGB3

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ITGB3

A gene on chromosome 17q25 that encodes an integrin beta chain protein (integrins are noncovalently associated transmembrane glycoprotein receptors, composed one of 18 different alpha and one of 8 different beta chains). The beta-3 chain partners with the alpha-IIb chain and acts as a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin, vitronectin and platelets. Beta-3 chain partnered with the alpha-5 chain is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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Myeloid CD markers CD Marker Result CD11b 3+ CD13 (LeuM7 pos CD14 (LeuM3) neg CD15 (LeuM1) neg CD33 (LeuM9) pos CD34 (My10) 2+ CD45 (HLE) pos CD61 (gp3a) 1+ CD64 neg CD71 pos CD117 pos HLA-DR neg Table 3.
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A new approach to teaching CIM: the CIM lab workstation

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