PIN is an outcome-driven kidney paired exchange system created to help living donor kidney transplant pairs identify more suitable matching pathways and support stronger transplant outcomes.
The system brings compatible and incompatible donor-recipient pairs into one structured compatibility-focused process to evaluate matching possibilities, improve compatibility, reduce unnecessary risks, and identify the right match for the right outcome.
For some pairs, PIN can create transplant possibilities that were not previously available. For others, it can help support stronger compatibility and better long-term outcomes.
PIN also believes transplantation should move with greater responsibility, flexibility, and human understanding — helping patients and donors access more suitable transplant pathways through a more patient-focused structure.
Because behind every donated kidney, there is a person giving a part of their life for another human being.
A simple, methodical process — designed for the day-to-day rhythm of transplant centers.
Patients can register directly, or be enrolled by their transplant center. Both compatible and incompatible donor-recipient pairs are welcome.
The algorithm discovers 2-, 3-, and 4-way exchange chains across all participating centers.
Centers review proposed cycles with full HLA matrix, antibody assessment, and risk indicators.
Surgeries are coordinated across centers and countries, all conducted simultaneously when possible.
Most patients waiting for a kidney already have someone willing to give one. The barrier is biology — and biology can be solved by matching at scale, not by waiting alone.
Pairs face HLA mismatches, ABO incompatibility, or donor-specific antibodies. Years pass on waiting lists while a willing donor sits beside them.
Pairs from any participating center enter a unified pool. The system finds 2-, 3-, and 4-way exchange chains automatically — including across borders.
Built for the day-to-day rhythm of transplant coordinators — from data entry to clinical decision packets ready for tumor board.
Class I and II HLA matching paired with MFI-aware antibody profiling. Forbidden mismatches identified automatically for every candidate pair.
Graph-based cycle detection finds longer exchange chains across all participating centers — chains traditional matching cannot reach by hand.
Centers across borders share a single anonymized pool. Geography becomes a variable, not a wall — dramatically expanding match opportunities.
Matches ranked by graft survival likelihood — not just first valid result. Smart scoring helps clinicians prioritize what matters.
I am very lucky to have had a chance meeting with wonderful people who are giving the gift of life to their loved ones. These individuals are the most important motivators that help me adore myself in my work. And therefore, I always tried to accomplish my best for the living donors.
I have evolved my technique based on what I've learned at Ohio State and adopted a different approach: retroperitoneal access for removing the kidney from donors. This technique helps the donors to be safe because the whole procedure avoids contact with intra-abdominal organs and therefore prevents abdominal complications, and I tried to train the young generations about this beneficial technique for the safety of the donor.
Read the full messagePre-registration helps us prepare matching pools and onboard centers in your region. We'll get back to you within a few working days.
Share your basic profile and we'll match you with a participating center.
Add your center to the cross-border PIN network.
