epimerization


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Related to epimerization: racemization, Mutarotation

epimerization

[‚e·pim·ə·rə′zā·shən]
(organic chemistry)
In an optically active compound that contains two or more asymmetric centers, a process in which only one of these centers is altered by some reaction to form an epimer.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
C-3 epimerization of vitamin D3 metabolites and further metabolism of c-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through c-1 or c-24 hydroxylation.
Mass spectrometric profiling of vitamin D metabolites beyond 25-hydroxyvitamin D
[9], in this processing step loss of (-)-epicatechin and (+)-catechin is partly attributed to heat-induced epimerization to (-)-catechin.
Cocoa polyphenols: can we consider cocoa and chocolate as potential functional food?
No epimerization could be detected for the two compounds investigated (Figure 1).
(R)-[alpha]-aminoadipic acid: a versatile precursor for the synthesis of D-amino acids
The reason might be that the main reason for loss of deltamethrin is evaporation, but the washing process or the drying in the sun after washing causes the epimerization. UV light is known to cause deltamethrin epimerization.
Evaluation of polyethylene-based long lasting treated bed net netprotect on anopheles mosquitoes, malaria incidence, and net longivity in western Kenya
Some of the reported catalysts suffer from disadvantages such as high acidity, the non-catalytic nature of the reagents, high temperatures, long reaction times or side isomer- ization, epimerization and rearrangement reactions [12-14].
Regioselective Nucleophilic Ring Opening of Epoxides Mediated by Novel Task- Specific Ionic Liquids; A Simple and Effective Method for Production of (Beta) -Hydroxy Azides and (Beta) -Hydroxy-Thiocyanates
The loss of moisture of sweet potato during storage may have influenced the occurrence of polymerization and epimerization of cell wall microfibrils leading to the thickening of the cell walls and subsequent release of carotenoids during in vitro digestion.
Changes in microstructure, beta carotene content and in vitro bioaccessibility of orange-fleshed sweet potato roots stored under different conditions
Otoliths as recorders of palaeoenvironments: comparison of radiocarbon age and isoleucine epimerization in Pleistocene golden perch Macquaria ambigua otoliths from Willandra Lakes.
Murray-Darling basin freshwater shells: riverine reservoir effect
These solutions were stored at -20[degrees]C for several days without apparent loss of detectable alkaloids, other than the expected epimerization. Working standard solutions (50-500 ng [mL.sup.-1]) in methanol/ water (2:1) were prepared daily.
Specificity of host-endophyte association in tall fescue populations from Sardinia, Italy
Epirubicin differs from adriamycin by the epimerization of the OH group in position 4' of the aminosugar moiety and has been shown to be less toxic during chemotherapeutic treatments against metastatic breast cancers (Ganzina 1983; reviewed by Hortabagyi 2000).
Mutagenic activity of idarubicin and epirubicin in the bacterium Salmonella typhimurium
The epimerization strongly decreases the compound's biologic efficacy; the anabolic potency of TbOH-17[alpha] is only about 5% of that of TbOH-17[beta] (9), and the affinity to the recombinant human androgen receptor (rhAR) is reduced to about 4% (10).
The fate of trenbolone acetate and melengestrol acetate after application as growth promoters in cattle: environmental studies. (Articles)
Feringa has made efficient use of 5-menthyl-oxy-2(5H)-furanones to provide enantiomerically pure synthons through "crystallization induced epimerization".
Industry: academic mix contributes to forum's success
The existence of D-isomers may be explained by racemization [22] of L-aspartic acid or epimerization of L-aspartyl residues in the polypeptides.
Thermal Synthesis of Polypeptides from N-Butyloxycarbonyl Oligopeptides Containing Aspartyl Residue at C-Terminus
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