VivaGel: Starpharma's women's health product - VivaGel BV is based on SPL7013, astodrimer sodium, a proprietary
dendrimer. VivaGel BV for bacterial vaginosis (BV), is available for sale under the brand name Betadine BVTM (Europe) and Fleurstat BVgel (Australia) and a new drug application has been submitted to the US FDA.
Let P[D.sub.1] denote PAMAM
dendrimers with trifunctional core unit generated by
dendrimer generations [G.sub.n] with n growth stages.
Organic nanocarriers are comprised of polymeric nanoparticles and lipid-based nanoparticles such as liposomes, nanoemulsions (e.g., micelles and reversed micelles),
dendrimers, and carbon-based nanocarriers (e.g., fullerenes and carbon nanotubes).
Positive aspects Site specific targeting Reduction in toxicity Controlled release Easy penetration in cells and tissues Protection of drug from enzymatic and chemical degradation
Dendrimers are new class of macromolecular architecture and are also being used as nanotechnology based cosmeceuticals for various applications like in hair care, skin care, and nail care.
Delivery of drugs, growth factors, or genetic material may be achieved following encapsulation in degradable (hydroxyapatite, gold,
dendrimer, and silica) or non-degradable [poly(L-lactide) (PLA) or poly(L-lactide-co-glycolic)] nano-spheres [14].
Starpharma Agrochemicals is comprised of key patents and technical know-how as well as a small number of staff dedicated solely to Priostar
dendrimers and agrochemicals operations.
Earlier it was shown by some authors how series of magnetic cobalt (Co) nanoparticles could be stabilized by a poly-amidoamine (PAMAM)
dendrimer [28], polyamine
dendrimers with a trimesyl core [29], and hydroxyl-terminated PAMAM
dendrimers [30].