Their study revealed that when induced by excessive amounts of
corticosterone, PDE4 causes depression and anxiety.
Resveratrol displayed neuroprotective effects against
corticosterone by inhibiting the expression of PDE4.
In in vitro studies, we found that treatment of PC12 cells with
corticosterone reduced their viability significantly (P<0.01, n=8) (Figure 5).
All kinds of stressors existing around broiler chickens can be mimicked by
corticosterone (Post et al., 2003).
The effects of restraint method, duration of restraint and body weight on plasma concentrations of
corticosterone, adrenaline, and noradrenaline are shown in Table 1.
Corticosterone and glucose levels, heart rate, and skin temperature via infrared thermography all have been used to quantify stress.
The Table 3 presented Spearman correlation (r) and p-value (p) of CC16, prolactin,
corticosterone, LDH, NF-[kappa]B and c-Jun, Zn, Cu concentration in serum and leukocytes numbers in bells sediments of BALF in rats after 5 days and 10 days of inhalation of WD dust and soluble form of dust (SWD).
Corticosterone plasmatic levels show something similar to that indicated above.
Serum concentrations of pregnenolone, 17a hydroxyprogesterone,
corticosterone, DHEA, and androstenedione were measured by LC-MS method using an Agilent 1200 Series HPLC system for HPLC (Agilent Technologies Inc., California, USA) and an AB Sciex API5000 tandem mass spectrometer (AB Sciex Pte.
Similarly, compared to the 2 groups without CS, patients with pituitary and ectopic subtypes of CS had higher plasma concentrations of 21-deoxycortisol (pituitary vs both groups, P < 0.0001; ectopic vs reference, P = 0.0004; ectopic vs rule-out, P = 0.0010),
corticosterone (pituitary vs both groups, P < 0.0001; ectopic vs reference, P < 0.0001; ectopic vs rule-out, P = 0.0004), and androstenedione (pituitary vs both groups, P < 0.0001; ectopic vs reference, P = 0.0007; ectopic vs rule-out, P = 0.0053), whereas there were no differences for those 3 steroids among patients with adrenal CS and the 2 groups without CS.
Studies in rats have shown that basal HPA axis activity is distinctly increased in lactation due to a rise in nadir levels of
corticosterone [17-20], while evening peak concentrations decrease [17, 21, 22], contributing to the flattening of the diurnal rhythm.